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Equine Joint Support Formula Two

September 2018 by Dr Georgina Learmonth
Georgina completed her Science Degree with majors in Biochemistry and Microbiology and, whilst undertaking a PhD at The University of Sydney she established Joint Performance and developed an oral joint health product based on comprehensive and sound research. Georgina has research interests in vaccine development and virology, as well as respiratory viral infections in horses, namely EHV-1/4. More recently, she completed her Medical Degree at The University of Sydney and is currently a trainee in emergency medicine.

Why choose Joint Performance?

Quite simply – our joint health supplements provide the optimal blend of Glucosamine and Chondroitin for your horse or dog. Joint support supplements can be thought of as nutrients or ‘food’ for joint health.

Our joint health supplements address the most important issue for your horse’s joint health and that is, maintenance and repair. Joint Performance products do this by providing quality glucosamine sulphate which is utilised by the joint to increase cartilage and fluid surrounding joints thereby improving joint function and slowing the progression of osteoarthritis.

Our carefully blended chondroitin sulphate directly protects joints from damage. Both these actives have the added benefit of impacting the inflammation cascade at specific points and this too helps your horse’s joints feel better and move better. Equine supplements have come a long way and our horse arthritis supplements provide the highest quality of joint therapy and just as importantly the best return on investment for you.

Joint Performance is Australia’s leading equine and canine joint health company since 2003. We are proudly Australian owned and are based in the Hawkesbury region of NSW.  We practice what we know best – joint health and providing the best supplement for joint health.

How does it work, and what are the active ingredients in Joint Performance Equine Joint Support Formula Two?

The joint requires particular substrates to meet normal daily repair and maintenance requirements. The key building block is Glucosamine Sulphate which is a GAG (glucosaminoglycan) precursor and a substrate for the biochemical pathway responsible for the production of macromolecules involved in joint articulation including chondroitin sulfate (CS) and hyaluronic acid (HA).

The rate-limiting step in the synthesis of these macromolecules is the level of glucosamine sulphate substrate available for incorporation into this biochemical pathway. By providing glucosamine sulphate we can push the biochemical pathway forward and, in effect, increase the synthesis of GAG’s and, thereby, provide a means for repair of articular cartilage.

Glucosamine Sulphate

Glucosamine Sulphate is a key building block used for the production of cartilage. Equine Joint Support Formula Two uses Glucosamine Sulphate as it is the only form of Glucosamine found naturally in healthy joints rather than the most commonly used Glucosamine Hydrochloride (HCL).

Studies suggest that the sulphated glucosamine increases synovial sulphate concentrations, which is very important for cartilage maintenance and repair, and low sulphate levels can slow this process. Notably, this is not corrected by sampling supplementing sulphate alone.

Chondroitin-4-Sulphate

Chondroitin-4-Sulphate is the major form of Chondroitin found in young healthy joints. It is one of the key components that gives cartilage its ability to absorb impact and resist wear.

Equine Joint Support Formula Two uses a high purity bovine derived Chondroitin-4-Sulphate due to its low molecular weight (small particle size) which is essential for efficient absorption, as opposed to the commonly used Chondroitin-6-Sulphate that is shark or marine-derived with a larger molecular weight.

Research studies suggest that Chondroitin-4-Sulphate plays a role in preventing destructive enzymes associated with cartilage breakdown as well as having a general anti-inflammatory action.

Is it an Anti-inflammatory?

Anti-inflammatories are only part of both acute and chronic management joint health. Important considerations are that anti-inflammatories only treat inflammation and do not provide active substrate that we know joint needs for maintenance and repair. That’s where Equine Joint Support Formula Two comes into play by providing quality glucosamine sulphate which is utilised by the joint to increase cartilage and fluid surrounding joints thereby improving joint function and slowing the progression of osteoarthritis.
Our carefully blended chondroitin sulphate directly protects joints from damage.  Both these actives have the added benefit of impacting the inflammation cascade at specific points and this too helps your horse’s joints feel better and move better.

How does it get into the joint?

Joints are a relatively simple structures composed of articular surfaces (moving surfaces) that come together within the joint capsule. It should be noted that there are no blood vessels, lymphatic channels, or nerves that enter or pass through joints.

Why is this important…?  This is how joints get their nutrition. It is through the process of loading and unloading (unstressed movement) of joints that creates changes in pressure within the joint capsule and facilitates the entry of nutrients across the synovial membrane.

Glucosamine Sulphate and Chondroitin sulphate move across the synovial membrane in the same way nutrients flow in and out of joints. This is not as simple as it sounds because for this process to work, you need to have the right type of molecule and it must be small enough to cross the membrane.

How often do you feed the supplement?

Equine Joint Support Formula Two is a highly palatable product that can simply be fed daily in a single feed.  It’s so palatable that horses will eat out our product from your hand … dogs too! 

For a 500kg horse:

  • Initial loading Dose: (2 Level Scoops) 50g per for the first 4- 6 weeks
  • Daily Maintenance Dose: 25g (1 Level Scoop) per day

Higher maintenance doses should be considered for horses in higher levels of work, significant joint health history, or advanced aging.

For additional dosage recommendations contact Joint Performance on 1300 105 104 or email – info@jointperformance.com.au.

Joint Performance products provide superior joint protection, maintenance and repair when used daily and can be safely and effectively combined with polysulphated pentosan injection schedules to further stimulate the protection and repair process.

Is there research behind the product?

There are huge volumes of research that span over three decades investigating the role of oral glucosamine sulphate and chondroitin sulphate. These studies are in humans and animals.
The most interesting thing is that we keep learning more about the fundamental role of oral glucosamine sulphate and chondroitin sulphate in joint health. What we have learnt, is that these oral products are a safe and effective step in caring for joints no matter what age or stage of life your horse is at.

My horse is not lame

The key aspect to joint health maintenance is not to wait until you have a problem. It’s about PREVENTION and trying to stop/delay the onset of joint degeneration. What does that look like in practice? It means you need to consider a number of factors and Equine Joint Support Formula 2 is one very important part of proactive joint health.  Other considerations include: weight; varied exercise (cross training); fitness; shoeing/trimming; stabling vs paddock.

What age should I start feeding the supplement?

Joint Support Formula 2 can be fed at any age, and the earlier the better.  The equine joint closes off when the horse reaches maturity, the cells responsible for making new healthy cartilage also decrease in number at this stage.  It makes sense to supplement with Equine Joint Support Formula 2 whilst there are as many cells as possible able to utilise this substrate and give the joint the best starting point. That said, anything to do with horses is expensive and we all want the best for them so starting your horse on Equine Joint Support Formula 2 is always going to be beneficial no matter what age or stage of life your horse is at.

What should I do in case of injury or lameness?

The action you take will depend on the circumstances around what ‘clinically’ you are seeing. 

Your first port of call for you or your horse should be professional medical advice, more so in the event of an acute trauma.  It’s important to understand that when there is trauma that involves laceration or puncture of the joint capsules, acute management will be the most important factor in avoiding infection and more specifically joint sepsis, thereby ensuring a good prognosis.